2022 Lexus RX 450h

$29,920

from

listings

$30K–$55K

price range

Download Infographic

Low$29,920

High$55,000

From$29,920

Avg Mileage54,286 mi

Fresh

Sourced from 70 dealer listings in the latest market snapshot as of Aug 2026

2022 Lexus RX 450h Trims

All Trims Combined

From$29,920

$30K–$55K

70 listings54,286 avg miles

F Sport

From$26,000

59 listings|$26K–$52K

2022 Lexus RX 450h Pricing

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Lexus RX 450h Fuel Economy

29–30mpg combined

29-31city

28hwy

$2,700-$2,800/yr

Fuel economy for the 2022 Lexus RX 450h ranges from 29 to 30 MPG combined across 2 setups. The table below breaks it down by trim so you know exactly what you're signing up for.

By Trim

RX 450h AWD - Automatic (AV-S6)

30mpg

3.5L 6-cyl · All-Wheel Drive

31 city28 hwy~$2,700/yr6/10 Average

RX 450h L AWD - Automatic (AV-S6)

29mpg

3.5L 6-cyl · All-Wheel Drive

29 city28 hwy~$2,800/yr6/10 Average

Source: U.S. Environmental Protection Agency (EPA)

Where to Find 2022 Lexus RX 450h

31States

36%in top 3

The biggest cluster of inventory is in California (22%), but the remaining listings are spread across 30 other states nationwide.

CACalifornia

15022%

TXTexas

528%

DCWashington DC

457%

FLFlorida

386%

WAWashington

335%

MDMaryland

315%

NYNew York

264%

NCNorth Carolina

264%

ILIllinois

254%

COColorado

233%

PAPennsylvania

233%

AZArizona

203%

UTUtah

193%

NJ14

DE11

NV11

MN10

MOMissouri

101%

GA9

OR9

CT9

OK9

NH8

MI8

MA7

TN7

KY6

ID5

AL5

OH5

HI4

Geographic distribution reflects all active listings for this model, not just 2022.

2022 Lexus RX 450h Buyer FAQ

What to know before you buy

Is the 2022 Lexus RX 450h a good car to buy?

The 2022 Lexus RX 450h has 0 recalls on record. Review the safety data and pricing breakdown above.

What's the gas mileage of the 2022 Lexus RX 450h?

Depending on configuration, the 2022 Lexus RX 450h delivers 29–30 MPG combined. Choose wisely. The full comparison shows how engine choice affects your wallet.