2006 Mercedes-Benz S500

$5,000

from

listings

$5K–$14K

price range

Download Infographic

Low$5,000

High$13,950

From$5,000

Avg Mileage108,333 mi

Fresh

Sourced from 6 active dealer listings as of May 2026

2006 Mercedes-Benz S500 Pricing

Price Trend

+28.1%

3 data pointsAs of Mar 26

Only 6 available nationwide.

Limited supply means limited chances. Get notified the moment new ones appear.

Get new listing alertsFrom $5/week

Mercedes-Benz S500 Fuel Economy

16–17mpg combined

14city

20-22hwy

$3,400-$3,600/yr

The 2006 Mercedes-Benz S500 delivers 16 to 17 MPG combined across 2 powertrain combinations. If fuel cost matters to you, pay attention to engine and drivetrain. The spread is significant.

By Trim

S500 - Automatic 7-spd

17mpg

5.0L 8-cyl · Rear-Wheel Drive

14 city22 hwy~$3,400/yr-1/10 Poor

S500 4matic - Automatic 5-spd

16mpg

5.0L 8-cyl · 4-Wheel or All-Wheel Drive

14 city20 hwy~$3,600/yr-1/10 Poor

Source: U.S. Environmental Protection Agency (EPA)

Where to Find 2006 Mercedes-Benz S500

29States

39%in top 3

California has the most inventory at 19%, with options spread across 29 states. Willing to ship? Your selection opens up significantly.

CACalifornia

11319%

FLFlorida

7413%

NYNew York

447%

NJNew Jersey

437%

ILIllinois

295%

GAGeorgia

295%

TXTexas

295%

DCWashington DC

264%

MDMaryland

254%

AZArizona

254%

PAPennsylvania

244%

DEDelaware

132%

TNTennessee

132%

NV9

WA9

NC9

MA7

IN7

OH7

OR6

AL5

CO5

CT5

AK4

WI4

MO4

NH3

KY3

OK3

Geographic distribution reflects all active listings for this model, not just 2006.

Buying a 2006 Mercedes-Benz S500?

Answers to common buyer questions

Is the 2006 Mercedes-Benz S500 a good car to buy?

The 2006 Mercedes-Benz S500 has its strengths and its watch-outs. Check the safety section for recall details and the pricing data to see if the numbers work for you.

What's the gas mileage of the 2006 Mercedes-Benz S500?

You'll get between 16 and 17 MPG combined from the 2006 Mercedes-Benz S500, depending on engine and drivetrain. That's a meaningful difference over time. The fuel economy table shows exactly which configs get what.