Fuel economy for the 2022 Lexus RX ranges from 21 to 23 MPG combined across 4 setups. The table below breaks it down by trim so you know exactly what you're signing up for.

By Trim

RX 350 - Automatic (S8)

23mpg

3.5L 6-cyl · Front-Wheel Drive

20 city27 hwy~$2,950/yr5/10 Average

RX 350 AWD - Automatic (S8)

22mpg

3.5L 6-cyl · All-Wheel Drive

19 city26 hwy~$3,050/yr5/10 Average

RX 350 L - Automatic (S8)

22mpg

3.5L 6-cyl · Front-Wheel Drive

19 city26 hwy~$3,050/yr5/10 Average

RX 350 L AWD - Automatic (S8)

21mpg

3.5L 6-cyl · All-Wheel Drive

18 city25 hwy~$3,200/yr4/10 Average

Source: U.S. Environmental Protection Agency (EPA)

Where to Find 2022 Lexus RX

30States

35%in top 3

The biggest cluster of inventory is in Texas (14%), but the remaining listings are spread across 29 other states nationwide.

TXTexas

1,46914%

FLFlorida

1,09811%

CACalifornia

1,03010%

DCWashington DC

7047%

NYNew York

5535%

MDMaryland

5145%

ILIllinois

4014%

NJNew Jersey

3744%

GAGeorgia

3624%

NCNorth Carolina

3443%

PAPennsylvania

3343%

MOMissouri

2873%

AZArizona

2462%

MN198

AL181

DE180

CT149

WA148

OK140

TN131

CO127

WI126

NH117

MI110

OH106

NV104

MA94

KY79

UT76

LA65

Geographic distribution reflects all active listings for this model, not just 2022.

Buying a 2022 Lexus RX?

Answers to common buyer questions

Is the 2022 Lexus RX a good car to buy?

The 2022 Lexus RX has 0 recalls on record. Review the safety data and pricing breakdown above.

What's the gas mileage of the 2022 Lexus RX?

Fuel economy ranges from 21 to 23 MPG combined. If you drive 15,000 miles a year, that gap is worth about $217 annually. See the fuel economy section for per-trim data.