Fuel economy for the 2022 Lexus RX ranges from 21 to 30 MPG combined across 6 setups. The table below breaks it down by trim so you know exactly what you're signing up for.

By Trim

RX 450h AWD - Automatic (AV-S6)

30mpg

3.5L 6-cyl · All-Wheel Drive

31 city28 hwy~$2,550/yr6/10 Average

RX 450h L AWD - Automatic (AV-S6)

29mpg

3.5L 6-cyl · All-Wheel Drive

29 city28 hwy~$2,600/yr6/10 Average

RX 350 - Automatic (S8)

23mpg

3.5L 6-cyl · Front-Wheel Drive

20 city27 hwy~$2,650/yr5/10 Average

RX 350 AWD - Automatic (S8)

22mpg

3.5L 6-cyl · All-Wheel Drive

19 city26 hwy~$2,800/yr5/10 Average

RX 350 L - Automatic (S8)

22mpg

3.5L 6-cyl · Front-Wheel Drive

19 city26 hwy~$2,800/yr5/10 Average

RX 350 L AWD - Automatic (S8)

21mpg

3.5L 6-cyl · All-Wheel Drive

18 city25 hwy~$2,950/yr4/10 Average

Source: U.S. Environmental Protection Agency (EPA)

Where to Find 2022 Lexus RX

32States

36%in top 3

The biggest cluster of inventory is in Texas (15%), but the remaining listings are spread across 31 other states nationwide.

TXTexas

1,47815%

FLFlorida

1,11711%

CACalifornia

98310%

DCWashington DC

6386%

NYNew York

5335%

MDMaryland

4545%

ILIllinois

3644%

NCNorth Carolina

3534%

GAGeorgia

3473%

PAPennsylvania

3433%

NJNew Jersey

3323%

MOMissouri

2723%

AZArizona

2392%

DEDelaware

2142%

MN178

AL175

CT148

WA145

WI132

OK124

TN122

CO112

MI109

NH108

OH102

OR91

MA90

NV82

UT73

ID60

LA52

Geographic distribution reflects all active listings for this model, not just 2022.

Buying a 2022 Lexus RX?

Answers to common buyer questions

Is the 2022 Lexus RX a good car to buy?

The 2022 Lexus RX has 0 recalls on record. Review the safety data and pricing breakdown above.

What's the gas mileage of the 2022 Lexus RX?

Fuel economy ranges from 21 to 30 MPG combined. If you drive 15,000 miles a year, that gap is worth about $750 annually. See the fuel economy section for per-trim data.